Efektivitas Pergerakan Sederhana Ekstrimitas Terhadap Penurunan Kadar Glukosa Pasien Diabetes Mellitus Tipe 2
DOI:
https://doi.org/10.55316/hm.v18i1.1209Keywords:
Diabetes mellitus; movements; blood glucose; physical activityAbstract
Low physical activity contributes to poor glycemic control in patients with type 2 diabetes mellitus (T2DM). Low-effort, practical exercises that can be taught by nurses can improve short-term glycemia, but evidence for single-session simple limb movements is limited. Objective: To evaluate the acute effects of simple limb movements on capillary blood glucose in patients with T2DM. A quantitative, single-group pre-test-post-test study was conducted using a sequential sample of 15 patients with T2DM. Participants performed seven types of simple limb movements with varying repetitions (3–20 repetitions). Capillary blood glucose was measured immediately before and after each movement using a glucometer (Glucotest). Changes were analyzed using the Wilcoxon signed-rank test; significance was set at p ? 0.05. Results show several movement-repetition combinations produced statistically and clinically significant acute reductions in blood glucose. Specifically, open-hand grip at 10 repetitions showed a mean reduction (? ? ?9, p = 0.012), and wrist flexion-extension at 16 repetitions produced a greater reduction (? ? ?37, p = 0.043). Other movements, particularly specific ankle exercises, showed large numerical reductions in some trials but with greater inter-participant variability and inconsistent statistical significance. No major adverse events were reported. Brief, simple extremity movements can produce acute reductions in capillary glucose among some patients with T2DM, suggesting feasibility as a nurse-led intervention that can be implemented in the community. These findings require confirmation through larger randomized trials with continuous glucose monitoring to determine clinical utility and optimal protocols
References
Adnan, Y., Hadju, V., Mallongi, A., & Ali, M. S. S. (2025). The Economic Cost of Type 2 Diabetes in Indonesia: A Systematic Review. Iranian Journal of Public Health, 54(10), 2139. https://doi.org/10.18502/IJPH.V54I10.20118
Antar, S. A., Ashour, N. A., Sharaky, M., Khattab, M., Ashour, N. A., Zaid, R. T., Roh, E. J., Elkamhawy, A., & Al-Karmalawy, A. A. (2023). Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments. Biomedicine & Pharmacotherapy, 168, 115734. https://doi.org/10.1016/J.BIOPHA.2023.115734
Bassin, S. R., & Srinath, R. (2023). The Impact of Physical Activity in Patients With Type 2 Diabetes. American Journal of Lifestyle Medicine, 19(1), 147. https://doi.org/10.1177/15598276231180541
Butt, M. D., Ong, S. C., Rafiq, A., Kalam, M. N., Sajjad, A., Abdullah, M., Malik, T., Yaseen, F., & Babar, Z. U. D. (2024). A systematic review of the economic burden of diabetes mellitus: contrasting perspectives from high and low middle-income countries. Journal of Pharmaceutical Policy and Practice, 17(1), 2322107. https://doi.org/10.1080/20523211.2024.2322107
Colberg, S. R., Sigal, R. J., Yardley, J. E., Riddell, M. C., Dunstan, D. W., Dempsey, P. C., Horton, E. S., Castorino, K., & Tate, D. F. (2016). Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association. Diabetes Care, 39(11), 2065. https://doi.org/10.2337/DC16-1728
Crasto, W., Patel, V., Davies, M. J., & Khunti, K. (2021). Prevention of Microvascular Complications of Diabetes. Endocrinology and Metabolism Clinics of North America, 50(3), 431–455. https://doi.org/10.1016/J.ECL.2021.05.005
de Almeida, J. A., Batalha, A. P. D. B., Santos, C. V. de O., Fontoura, T. S., Laterza, M. C., & da Silva, L. P. (2024). Acute effect of aerobic and resistance exercise on glycemia in individuals with type 2 diabetes: Systematic review and meta-analysis. Brazilian Journal of Physical Therapy, 29(1), 101146. https://doi.org/10.1016/J.BJPT.2024.101146
Dehdari, T., Shahraki-Sanavi, F., Nasiri, A., Nouri, R., Moghaddam, A. A., & Mohammadi, M. (2025). Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran. Health Science Reports, 8(4), e70658. https://doi.org/10.1002/HSR2.70658
Gidudu, M., Nandutu, L., Ankunda, R., Epuitai, J., Lulenzi, J., Ssenyonga, L. V. N., Gavamukulya, Y., & Nabirye, R. C. (2025). Factors affecting lifestyle modification among adults with type II diabetes mellitus attending care at Mbale Regional Referral Hospital in Mbale City, Eastern Uganda: A Mixed Methods Study. Journal of Public Health Research, 14(4), 22799036251395268. https://doi.org/10.1177/22799036251395268
Johnson, E. L., Feldman, H., Butts, A., Chamberlain, J., Collins, B., Doyle-Delgado, K., Dugan, J., Leal, S., Rhinehart, A. S., Shubrook, J. H., & Trujillo, J. (2020). Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers. Clinical Diabetes?: A Publication of the American Diabetes Association, 38(1), 10. https://doi.org/10.2337/CD20-AS01
Liberty, I. A., Kurniawan, F., Wijaya, C. N., Soewondo, P., & Tahapary, D. L. (2024). The Impact of Lifestyle Changes on the Prevalence of Prediabetes and Diabetes in Urban and Rural Indonesia: Results from the 2013 and 2018 Indonesian Basic Health Research (RISKESDAS) Survey. Diabetology, 5(6), 537–553. https://doi.org/10.3390/DIABETOLOGY5060039/S1
Logan, B. K., Larsen, R., Sacre, J. W., Cohen, N. D., Lambert, G. W., Wheeler, M. J., Owen, N., Kingwell, B. A., Dunstan, D. W., & Dempsey, P. C. (2025). Interrupting prolonged sitting reduces postprandial GIP but not GLP?1 responses in type 2 diabetes. Diabetes, Obesity & Metabolism, 27(11), 6771. https://doi.org/10.1111/DOM.70046
Richter, E. A. (2020). Is GLUT4 translocation the answer to exercise-stimulated muscle glucose uptake? American Journal of Physiology - Endocrinology and Metabolism, 320(2), E240. https://doi.org/10.1152/AJPENDO.00503.2020
Ru, E., Ec, O., & Gi, M. (2025). Complications Associated with Type 2 Diabetes Mellitus, Pathophysiology, Diagnosis and Management: A Concise Review of Current Literature. Saudi J Biomed Res, 10(7), 201–244. https://doi.org/10.36348/sjbr.2025.v10i07.001
Smith, A. D., Crippa, A., Woodcock, J., & Brage, S. (2016). Physical activity and incident type 2 diabetes mellitus: a systematic review and dose–response meta-analysis of prospective cohort studies. Diabetologia, 59(12), 2527–2545. https://doi.org/10.1007/S00125-016-4079-0
Sun, H., Saeedi, P., Karuranga, S., Pinkepank, M., Ogurtsova, K., Duncan, B. B., Stein, C., Basit, A., Chan, J. C. N., Mbanya, J. C., Pavkov, M. E., Ramachandaran, A., Wild, S. H., James, S., Herman, W. H., Zhang, P., Bommer, C., Kuo, S., Boyko, E. J., & Magliano, D. J. (2022). IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Research and Clinical Practice, 183. https://doi.org/10.1016/j.diabres.2021.109119
Syeda, U. S. A., Battillo, D., Visaria, A., & Malin, S. K. (2023). The importance of exercise for glycemic control in type 2 diabetes. American Journal of Medicine Open, 9, 100031. https://doi.org/10.1016/J.AJMO.2023.100031
Wahidin, M., Achadi, A., Besral, B., Kosen, S., Nadjib, M., Nurwahyuni, A., Ronoatmodjo, S., Rahajeng, E., Pane, M., & Kusuma, D. (2024). Projection of diabetes morbidity and mortality till 2045 in Indonesia based on risk factors and NCD prevention and control programs. Scientific Reports 2024 14:1, 14(1), 5424-. https://doi.org/10.1038/s41598-024-54563-2
Yu, H. J., Hong, D., Kim, K., Heo, J. H., Cho, D. H., Hashimoto, Y., & Yun, J. S. (2025). Optimizing Physical Activity Strategies for Older Adults with Diabetes. Diabetes & Metabolism Journal, 49(6), 1178. https://doi.org/10.4093/DMJ.2025.0967










