Proses Penyembuhan Luka Diabetik Yang Menggunakan Terapi Ozon Pada Pasien Dengan Diabetes Mellitus
DOI:
https://doi.org/10.55316/hm.v17i2.1142Keywords:
Diabetes Mellitus, Diabetic Wounds, Ozone TherapyAbstract
Diabetic wounds are the most common complication of diabetes mellitus. Ozone therapy is a complementary therapy that can accelerate and improve the healing process of diabetic wounds. The advantages of ozone therapy are its antimicrobial effects through increased tissue oxygenation, stimulation of angiogenesis, and modulation of the inflammatory response. The purpose of this study was to determine how diabetic wounds are treated after ozone therapy. The design used was a descriptive case study using two clients with diabetes mellitus and diabetic wound complications who visited the Mojopahit Wocare Clinic in Mojokerto Regency as research subjects. The results of this study were obtained in subject I, wounds closed faster and regenerated well with a reduction in the area of ??the wound in the subject of approximately 2.13 cm2/day with an estimated wound healing time of 10 weeks, and in subject II, wounds closed faster and regenerated well with a reduction in the area of ??the wound in the subject of approximately 4.67 cm2/day with an estimated wound healing time of 7 weeks. Therefore, ozone therapy is very helpful in the healing process of diabetic wounds and for a nurse to have a role as an educator in providing information, providing services and helping clients in increasing the level of health knowledge, especially about ozone therapy for healing diabetic wounds.
References
Akkus, G., & Sert, M. (2022). Diabetic foot ulcers: A devastating complication of diabetes mellitus continues non-stop in spite of new medical treatment modalities. World Journal of Diabetes, 13(12), 1106. https://doi.org/10.4239/WJD.V13.I12.1106
Anzolin, A., Da Silveira-Kaross, N., & Bertol, C. (2020). Ozonated oil in wound healing: what has already been proven? Medical Gas Research, 10(1), 54. https://doi.org/10.4103/2045-9912.279985
Astasio-Picado, Á., Babiano, A. Á., López-Sánchez, M., Lozano, R. R., Cobos-Moreno, P., & Gómez-Martín, B. (2023). Use of Ozone Therapy in Diabetic Foot Ulcers. Journal of Personalized Medicine, 13(10), 1439. https://doi.org/10.3390/JPM13101439
Bodman, M. A., Dreyer, M. A., & Varacallo, M. A. (2024). Diabetic Peripheral Neuropathy. The Diabetes Textbook: Clinical Principles, Patient Management and Public Health Issues, Second Edition, 923–937. https://doi.org/10.1007/978-3-031-25519-9_56
Boulton, A. J. M., & Whitehouse, R. W. (2023). The Diabetic Foot. Https://Pubmed.Ncbi.Nlm.Nih.Gov/28121117/. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK409609/
Chawla, A., Chawla, R., & Jaggi, S. (2016). Microvasular and macrovascular complications in diabetes mellitus: Distinct or continuum? Indian Journal of Endocrinology and Metabolism, 20(4), 546. https://doi.org/10.4103/2230-8210.183480
Dayya, D., O’Neill, O. J., Huedo-Medina, T. B., Habib, N., Moore, J., & Iyer, K. (2022). Debridement of Diabetic Foot Ulcers. Advances in Wound Care, 11(12), 666. https://doi.org/10.1089/WOUND.2021.0016
Goyal, R., Singhal, M., & Jialal, I. (2023). Type 2 Diabetes. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513253/
Hammer, B., Fletcher, F., & Hibbert, A. (2017). Participant observation: Enhancing the impact measurement in community based participatory research. Qualitative Report, 22(2), 439–455. https://doi.org/10.46743/2160-3715/2017.2553
Hossain, M. J., Al-Mamun, M., & Islam, M. R. (2024). Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused. Health Science Reports, 7(3), e2004. https://doi.org/10.1002/HSR2.2004
Idrees, M., Khan, I., Ullah, A., Shah, S. M. M., Ullah, H., Khan, M. A., … Nadeem, T. (2024). Bacterial spectrum from diabetic foot Ulcers: A study of antibiotic resistance patterns and phylogenetic diversity. Journal of King Saud University - Science, 36(8), 103320. https://doi.org/10.1016/J.JKSUS.2024.103320
Kushmakov, R., Gandhi, J., Seyam, O., Jiang, W., Joshi, G., Smith, N. L., & Khan, S. A. (2018). Ozone therapy for diabetic foot. Medical Gas Research, 8(3), 111. https://doi.org/10.4103/2045-9912.241076
Lima e Silva Filho, M., Paggiaro, A. O., Fernandes de Carvalho, V., & Gemperli, R. (2024). Ozone therapy as a treatment for diabetic foot ulcers: a systematic review and meta-analysis. Journal of Wound Care, 33(12), 958–967. https://doi.org/10.12968/JOWC.2022.0189
Maqbool, N., Dar, A. H., Kumar Dash, K., Srivastava, S., Pandey, V. K., Shams, R., … Manzoor, S. (2024). Ozonation effects on structural and functional characteristics of starch. Future Foods, 9, 100334. https://doi.org/10.1016/J.FUFO.2024.100334
Ma’rifah, A. (2018). ORIGINAL RESEARCH JAPANESE ANTS (TENEBRIO MOLITOR) STABILIZE BLOOD SUGAR LEVELS FOR DIABETICS: THE CURRENT ISSUE OF HERBAL MEDICINE IN INDONESIA. Retrieved from http://ijnms.net/index.php/ijnms
McDermott, K., Fang, M., Boulton, A. J. M., Selvin, E., & Hicks, C. W. (2022). Etiology, Epidemiology, and Disparities in the Burden of Diabetic Foot Ulcers. Diabetes Care, 46(1), 209. https://doi.org/10.2337/DCI22-0043
Meriyansyah, M., Darmawansyah, D., & Fauzi, Y. (2024). A Correlation Between Education And Family Support With Regular Control Of Blood Sugar Levels In Diabetes Mellitus Patients At Hasanudin Damrah Manna Hospital. Journal of International Public Health, 2(2), 39–42. https://doi.org/10.37676/JIPH.V2I2.5752
Mieczkowski, M., Mrozikiewicz-Rakowska, B., Kowara, M., Kleibert, M., & Czupryniak, L. (2022). The Problem of Wound Healing in Diabetes—From Molecular Pathways to the Design of an Animal Model. International Journal of Molecular Sciences, 23(14), 7930. https://doi.org/10.3390/IJMS23147930
Nurjanah, M. H., Wijaya, A. F., Meri, M., Tilarso, D. P., & Siswidiani, M. D. (2023). The Relationship between HbA1c and Glucosuria in Diabetes Mellitus (DM) Patients. Medicra (Journal of Medical Laboratory Science/Technology), 6(2), 84–88. https://doi.org/10.21070/medicra.v6i2.1727
Pemayun, T. G. D., & Naibaho, R. M. (2017). Clinical profile and outcome of diabetic foot ulcer, a view from tertiary care hospital in Semarang, Indonesia. Diabetic Foot & Ankle, 8(1), 1312974. https://doi.org/10.1080/2000625X.2017.1312974
Pinto, L., Tapia-Rodríguez, M. R., Baruzzi, F., & Ayala-Zavala, J. F. (2023). Plant Antimicrobials for Food Quality and Safety: Recent Views and Future Challenges. Foods, 12(12), 2315. https://doi.org/10.3390/FOODS12122315
Soewondo, P., Ferrario, A., & Tahapary, D. L. (2013). Challenges in diabetes management in Indonesia: a literature review. Globalization and Health, 9(1), 63. https://doi.org/10.1186/1744-8603-9-63
Sutkowska, E., Sutkowski, K., Sokołowski, M., Franek, E., & Dragan, S. (2019). Distribution of the Highest Plantar Pressure Regions in Patients with Diabetes and Its Association with Peripheral Neuropathy, Gender, Age, and BMI: One Centre Study. Journal of Diabetes Research, 2019, 7395769. https://doi.org/10.1155/2019/7395769
Xue, W., Macleod, J., & Blaxland, J. (2023). The Use of Ozone Technology to Control Microorganism Growth, Enhance Food Safety and Extend Shelf Life: A Promising Food Decontamination Technology. Foods, 12(4), 814. https://doi.org/10.3390/FOODS12040814
